Mechanisms and Treatment of Postoperative Cognitive Dysfunction in Aged Mice
Overview
During my undergraduate medical training, I worked with Professor Pingliang Yang to study cognitive impairment after surgery in aged mice, focusing on neuroinflammation and neuronal injury.
Approach
I established the model by performing splenectomy under anesthesia and assessed learning and memory with the Morris water maze. I also assisted with patch-clamp recordings to examine neuronal activity.