Coal Dust Exposure and Cognitive Impairment in Miners

Overview

Working with Professor Jing Zhang and Mei Zhang, I contributed to a study of cognitive impairment in coal miners. We investigated its association with coal dust exposure and the inflammatory mechanisms that might explain it.

Approach

The study used clinical data from miners and experimental models of coal dust exposure. I analyzed transcriptomic data and helped organize clinical records, exposure data, questionnaires and cognitive assessments, including data entry and quality checks.

Published study

The paper reports cognitive impairment associated with coal dust exposure and experimental evidence implicating IL6/ERK1/2/SP1 signaling.

Published in Science of the Total Environment, 2024.